無標題文件
無標題文件
  Jia-Yi Wang English Introduction  
 

姓名

王家儀 (Jia-Yi Wang)    
研究室地點 醫學綜合大樓 9 樓 生理學科 (辦公室、實驗室在12樓 醫科所)
聯絡方式

電話: (02)2736-1661ext. 3412;傳真: (02)2377-8620

電子郵件: jywang2010@tmu.edu.tw

職稱 教授
學歷 美國明尼蘇達大學藥理學博士
經歷

北醫校級神經醫學研究中心執行長(2019/1-迄今)

臺北醫學大學生理學科主任 (2010/4-2018/2)

臺北醫學大學醫科所教授 (2010/2-迄今)

國防醫學院生理學科()科主任(所長) (2002/3-2008/7)

國防醫學院生理學科副教授、教授 (1985/1-2010/1)

美國伊利諾州大學藥理系博士後研究 (1984/1-1984/12)

美國國家研究院藥物濫用研究所客座研究員 (2000/8-2001/1)

榮譽與服務

中國生理學會現任理事(連任第17-24)

中華民國基礎神經科學學會理事

(連任第34678910)

台灣神經創傷學會理事

財團法人高等教育評鑑中心基金會(教育部委託)

實地訪查委員

考選部題庫試題審查(召集人)

考選部專門職業及技術人員高等考試命題委員

教師陞等著作審查委員(教育部、台大醫學院、

台北醫學大學、國立陽明大學、台大生命科學院、

師大生命科學系、政大生命科學系、慈濟大學

中國醫藥醫學大學…)

國內外期刊論文、研究計畫審查委員

研究專長

神經損傷與退化、保護與再生、氧化與抗氧化醫學、細胞訊息傳遞學、神經免疫

研究計畫

計畫名稱

1.

腦創傷引起急性肺損傷:促發效應造成後續神經後遺症和跨器官損傷之機制(MOST 104-107)

2.

Thalidomide新衍生藥與p53新抑制劑用於治療急性腦創傷:投藥 途徑、劑量效果及多重

  制之探討(MOST 104-107)
3.

腦外傷之新穎藥物治療策略(MOST 101-104)

4.

探討細胞自噬作用與血基質氧化酶酶(第一型及第二型)於腦損傷之角色:從活體到細胞機制

  (三年計畫)   (NSC99-102)
5.

腦神經受體影像在注意力欠缺過動症轉譯研究-總計畫暨子計畫三:過動症受體造影效性

  及療效評估(NSC)
6. 顆粒性群落剌激因子於腦缺血動物模式對水通道蛋白之基因及蛋白質表現之影響

 

(TMU-WFH)

7.

顱內出血和頭部外傷患者之顱內壓、昏迷指數與腦脊髓液中發炎介質因子及糖分濃度與病

 

情嚴重度和預後評估的相關性(TIMHH)

 

論文發表

期刊論文:

1

Batsaikhan, B., Wang, J.Y., Scerba, M.T., Tweedie, D., Greig, N.H., Miller, J.P., Hoffer, B.J., Lin, C.T., Wang, J.Y. * (2019). Post-Injury neuroprotective effects of the thalidomide analog 3,6’-dithiothalidomide on traumatic brain injury. Int J Mol Sci 20 (3): 502計畫編號MOST104-2923-B-038- 001-MY3. 本人為通訊作者

2

Huang, Y.N., Yang, L.Y., Greig, N.H, Lai, C.C., Wang, J.Y.* (2018). Neuroprotective effects of pifithrin-α against traumatic brain injury in the striatum through suppression of neuroinflammation, oxidative stress, autophagy, and apoptosis. Sci Report 8(1): 2368-2381. 計畫編號MOST104-2923-B-038- 001-MY3 本人為通訊作者

3

Lin, Y.F., Liu T.T., Hu, C.H., Chen, C.C., Wang, J.Y.* (2018). Expressions of chemokines and their receptors in the brain after heat stroke-induced cortical damage. J Neuroimmunol 318:15-20. 計畫編號MOST104-2923-B-038- 001-MY3 本人為通訊作者

4 Huang, Y.N., Yang, L.Y., Wang, J.Y., Lai, C.C., Chiu, C.T., Wang, J.Y.* (2017). L-Ascorbate protects against methamphetamine-induced neurotoxicity of cortical cells via inhibiting oxidative stress, autophagy, and apoptosis. Molecular Neurobiology. 54(1), 125-136. 計畫編號MOST-103-2321-B-038-002 and MOST-104-2320-B-038-057-MY3. 本人為通訊作者
5 Liao, K.H., Sung, C.W., Huang, Y.N., Li, W.J., Yu, P.C., Wang J.Y.*(2017).Therapeutic potential of drugs targeting pathophysiology of intracerebral hemorrhage: From animal models to clinical applications. Current Pharmaceutical Design, 2017, 23, 1-14 計畫編號 MOST104-2923-B-038-001- MY3 (1–3 & 2–3) 本人為通訊作者
6 Yang, L.Y., Greig, N.H., Huang, Y.N., Hsieh, T.H., Tweedie, D., Yu, Q.S., Hoffer, B.J., Luo, Y, Kao, Y.C., Wang, J.Y.* (2016). Post-traumatic administration of the p53 inactivator pifithrin-α oxygen analogue reduces hippocampal neuronal loss and improves cognitive deficits after experimental traumatic brain injury. Neurobiology of Disease. 96: 216-226. 計畫編號MOST104-2923-B-038- 001-MY3 本人為通訊作者
7 Chiu, C.C., Liao, Y.E., Yang, L.Y., Wang, J.Y., Tweedie, D., Karnati, H.K., Greig, N.H., Wang, J.Y.* (2016). Neuroinflammation in animal models of traumatic brain injury. J Neurosci Methods. 272: 38-49. 計畫編號MOST104-2923-B-038-001-MY3
8 Wang, J.Y., Chiu, C.C., Huang, Y.N., Chou, S.Y., Tweedie, D., Luo, W., Pick, C.G., Luo, Y., Hoffer, B.J., Greig, NH*, Wang, J.Y.*(2016). Pomalidomide mitigates neuronal loss, neuroinflammation and behavioral impairments induced by traumatic brain injury in rat. Journal of Neuroinflammation. 13 :168-184. 計畫編號 (MOST104-2923-B-038-001-MY3) 本人為通訊作者
9 Liao, K.H., Chu, S.F., Sung, C.W., Chiang, Y.H., Hoffer, B., Ou, J.C., Chen, K.Y., Tsai, S.H., Lin, C.M., Chen, G.S., Li, W.J., Chiu, W.T., Wang, J.Y.*(2016). Reduced power spectra of heart rate variability are correlated with anxiety in patients with mild traumatic brain injury. Psychiatry Research. 243:349-356  計畫編號MOST-103-2321-B-038-002 and MOST-104-2923-B-038-001-MY3
10 Chen, G.S., Liao, K.H., Bien, M.Y., Peng, G.S., Wang, J.Y.* (2016). Increased risk of post-trauma stroke following traumatic brain injury-induced acute respiratory distress syndrome. J Neurotrauma. 33 (13):1263-1269. 計畫編號MOST 104-2320-B-038-057-MY3. 本人為通訊作者
11 Yang, L.Y., Huang, C.C., Chiu, W.T., Huang, L.T., Lo, W.C., Wang, J.Y.*(2016). Association of traumatic brain injury in childhood and attention-deficit/hyperactivity disorder: a population-based study. Pediatric Research. 80:356-362. 計畫編號 MOST-104-2320-B-038-057-MY3 and MOST- 104- 2923-B-038-001- MY3  本人為通訊作者
12 Sung, C.W., Chen, K.Y., Chiang, Y.H., Chiu, W.T., Ou, J.C., Lee, H.C., Tsai, S.H., Lin, J.W., Yang, C.M., Tsai, Y.R., Liao, K.H., Chen, G.S., Wang, J.Y*. (2016). Heart rate variability and serum level of insulin growth factor-1 are correlated with emotional disorders in patients suffering a mild traumatic brain injury. Clinical Neurophysiology 127.1629-1638.計畫編號MOST-103-2321-B-038-002 and MOST-104-2320-B-038-057-MY3.本人為通訊作者
13 Sung, C.W., Lee, H.C., Chiang, Y.H., Chiu, W.T., Chu, S.F., Ou, J.C., Tsai, S.H., Liao, K.H., Lin, C.M., Lin, J.W., Chen, G.S., Li, W.J., Wang, J.Y.* (2016). Early dysautonomia detected by heart rate variability predicts late depression in female patients following mild traumatic brain injury. Psychophysiology.53:455-464. 計畫編號 MOST-103-2321-B-038-002 and MOST 104-2320-B-038-057-MY3. 本人為通訊作者
14 Chiu, C.T., Wen, L.L., Pao, H.P., Yang, L.Y., Huang, Y.N., Wang, J.Y.* (2016) Reparixin attenuates neuronal injury in experimental Klebsiella pneumoniae meningoencephalitis through dual effects on neuroprotection and neuroinflammation. Neuropathology and Applied Neurobiology. 42(4):326-343
15 Huang, Y.N., Ho, Y.J., Lai, C.C., Chiu, C.T., Wang, J.Y.*(2015). 1,25-Dihydroxyvitamin D3 attenuates endotoxininduced production of inflammatory mediators by inhibiting MAPK activation in primary cortical neuron-glia cultures. J Neuroinflammation.(12):147-158. 計畫編號MOST-103-2321-B-038-002 and MOST-104-2320-B-038-057- MY3. 本人為通訊作者
16 Yang, L.Y., Chu, Y.H., Tweedie, D., Yu, Q.S., Pick, C.G., Hoffer, B.J., Greig, N.H., Wang, J.Y.*(2015). Post-trauma administration of the pifithrin-α oxygen analogue improves histological and functional outcomes after experimental traumatic brain injury. Exp Neurol 269: 56-66計畫編號MOST 103-2321-B-038-002. 本人為通訊作者.
17 Chen, G.S., Huang, K.F., Huang, C.C. and Wang, J.Y.* (2015) Thaliporphine derivative improves acute lung injury after traumatic brain injury. BioMed Res Int(formerly titled Journal of Biomedicine and Biotechnology) 2015, 729831計畫編號MOST 103-2321-B-038-002. 本人為通訊作者.
18 Sung, C.W., Chen, K.Y., Chiang, Y.H., Chiu, W.T., Ou, J.C., Lee, H.C., Tsai, S.H., Lin, J.W., Yang, C.M., Tsai, Y.R., Liao, K.H., Chen, G.S., Wang, J.Y*. (2016). Heart rate variability and serum level of insulin growth factor-1 are correlated with emotional disorders in patients suffering a mild traumatic brain injury. Clinical Neurophysiology 127.1629-1638. (http://dx.doi.org/10.1016/j.clinph.2015.08.006) 計畫編號MOST-103-2321-B-038-002 and MOST-104-2320-B-038-057-MY3.本人為通訊作者
19 Liew, H.K., Kuo, J.S., Wang, J.Y.*, Pang, C.Y. *(2015) Granulocyte-colony stimulating factor increases cerebral blood flow via a no surge mediated by Akt/eNOS pathway to reduce ischemic injury. The Scientific World Journal 2015:657932. doi:10.1155/2015/657932 計畫編號NSC96-2320-B-016-014-MY3本人為通訊作者
20 Hsieh, T.H., Huang, Y.Z., Chen, J.J., A Rotenberg, Chiang, Y.H., Chang, Chen W.S., Chang, V., Wang, J.Y.*, Peng, C.W.* (2015). Novel use of theta burst cortical electrical stimulation for modulating motor plasticity in rats. J Med Biol Eng. (35):62-68. 本人為通訊作者 
21 Wang, H.W.*, Chao, P.Z., Lee, F.P., Wang, J.Y.*(2015). Benzydamine oral spray inhibiting parasympathetic function of tracheal smooth muscle. Clin Exp Otorhinolaryngo. (8):65-68. 本人為通訊作者 
22 Chiu, C.T., Wen, L.L., Pao, H.P., Yang, L.Y., Huang, Y.N., Wang, J.Y.* (2015). Reparixin attenuates neuronal injury in experimental Klebsiella pneumoniae meningoencephalitis through dual effects on neuroprotection and neuroinflammation. Neuropathology and Applied Neurobiology.(in press):-. 計畫編號MOST  103-2321-B-038-002本人為通訊作者
23 Liu, K.H., Yang, S.T., Lin, Y.K., Lin, J.W., Lee YH, Wang, J.Y., Hu, C.J., Lin, E.Y., Chen, S.M., Then, C.K., Shen, S.C.(2015). Fluoxetine, an antidepressant, suppresses glioblastoma by evoking AMPAR-mediated calcium dependent apoptosis. Oncotarget.(6):5088-5101. 計畫編號 MOST-103-2321-B-038-002.  
24

Baratz, R, Tweedie, D, Wang, J.Y., Rubovitch, V., Luo, W., Hoffer, B.J., Greig, N.H., Pick, C.G. (2015)Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in mice. J Neuroinflamm 12:45-58.計畫編號 MOST-103-2321-B-038-002.

25 Lu, K.T., Huang, T.C., Wang, J.Y., You, Y.S., Chou, J.L., Chan, M.W., Wo, P.Y., Amstislavskaya, T.G., Tikhonova, M.A. and Yang, Y.L. (2014).  NKCC1 mediates traumatic brain injury-induced hippocampal neurogenesis through CREB phosphorylation and HIF-1alpha expression. Pflugers Archiv : European Journal of Physiology. 2014  Sep 9. [Epub ahead of print] PMID:25201604  
26 Wang, J.Y., Lee, C.T., Wang, J.Y. (2014) Nitric oxide plays a dual role in the oxidative injury of cultured rat microglia but not astroglia. Neuroscience. (281):164-177.計畫編號MOST 103-2321-B-038-002. 本人為第一作者
27 Huang, K.F., Hsu, W.C., Hstao, J.K., Chen, G.S., Wang, J.Y.* (2014) Collagen-Glycosaminoglycan matrix implantation promotes angiogenesis following surgical brain Trauma. BioMed Res Int(formerly titled Journal of Biomedicine and Biotechnology) 2014:672409 計畫編號MOST 103-2321-B-038-002. 本人為通訊作者.  
28 Huang, Y.N., Lai, C.C., Chiu, C.T., Lin, J.J., Wang, J.Y.* (2014). L-Ascorbate attenuates the endotoxin-induced production of inflammatory mediators by inhibiting MAPK activation and NF-κB translocation in cortical neurons/glia cocultures. PLoS One: 9: e97276. 計畫編號(NSC99-2320-B-038-006-MY3, NSC 101-2321-B-038-003) 本人為通訊作者.
29 Hsieh, T. H., Huang, Y. Z., Rotenberg, A., Pascual-Leone, A., Chiang, Y. H., Wang, J. Y., Chen, J. J.(2014). Functional dopaminergic neurons in substantia nigra are required for transcranial magnetic stimulation-induced motor plasticity. Cereb Cortex. (2014 Jan 22. [Epub ahead of print]. 計畫編號NSC 99-2320-B-038-006-MY3.
30 Rachmany, L., Tweedie, D., Rubovitch, V., Yu Q.S., Li, Y., Wang, J-Y., Pick, C.G., Greig, N.H. (2014). Cognitive impairments accompanying rodent mild traumatic brain injury involve p53-dependent neuronal cell death and are ameliorated by the tetrahydrobenzothiazole PFT-α. PLoS One (8):e79837-e79837. 計畫編號NSC 101-2321-B-038-003
31 Tai, Y.T., Lee, W.Y., Lee, F.P., Lin, T.J., Shih, C.L. Wang, J. Y.* , Chiu, W.T., Hung, K.S. (2014). Low dose of valproate improves motor function after traumatic brain injury. BioMed Research International. (formerly titled Journal of Biomedicine and Biotechnology) 2014: 980657 計畫編號NSC 102-2321-B-038-003本人為通訊作者.  
32 Chang, B.C., Liu, D.H., Chang, J.L., Lee, S.H., Wang, J.-Y.* (2014). Plantar pressure analysis of accommodative insole in older people with metatarsalgia. Gait & Posture, 39(1), 449-454. 計畫編號(NSC 101-2321-B-038-003) 本人為通訊作者.
 

 

 
無標題文件

連絡地址:(11031)臺北市信義區吳興街250號 醫學綜合大樓9F | 電話: 27361661#3714| E-Mail : tmupy@tmu.edu.tw
建議最佳解析度: 1024 * 768 或更高 | 建議使用瀏覽器: Internet Explorer 6.0 以上 | 臺北醫學大學生理學科 | 最後更新:2020/12/25